Protocol Accrual Lifecycle

Protocol Accrual Lifecycle Wheel

Most clinical trials follow a sequence—from developing a protocol through recruiting participants to closing the trial and analyzing the results. We think of this as the protocol's life cycle.  At every stage of the lifecycle, accrual matters. 

AccrualNet™ can help by providing accrual strategies for you to consider at each stage, and carefully selected resources and tools for you to use.  You can explore the Protocol Accrual Lifecycle here with links to related journal articles and resources, or download a PDF version to use offline and share with colleagues.

STAGE 1: Developing a Trial

Successful clinical trial accrual begins at the protocol writing stage. The earlier in the trial's lifecycle that you plan for accrual, the more likely the trial is to recruit.  Learn More....

STAGE 2: Selecting & Preparing to Open a Trial

Should this clinical trial be opened at my site?” This is an important question and the answer isn't always "Yes!"  Learn More....

STAGE 3: Recruiting and Communicating with Participants

The trial is open for enrollment. Now what? You should be finding, meeting, and establishing relationships with participants. But how?  Learn More....

STAGE 4: Implementing the Trial

Managing recruitment and retention is a vital component of overall trial management. As recruitment, enrollment, and retention activities are underway, the trial team must keep communications and logistics running smoothly.  A Recruitment and Retention Plan can help.  Learn More....

STAGE 5: Evaluating Accrual and Reporting Lessons Learned

The closing of a trial is a time to take stock—to understand both what went well and what did not. Use the lessons learned to build the knowledge and capacity of your team and to strengthen future recruitment efforts.  Learn More....