A Comprehensive Program for the Enhancement of Accrual to Clinical Trials

Posted: Jan 25, 2017
Ann Surg Oncol. 23. 2146.
KEYWORDS: Level of Clinical Trials Knowledge or Awareness, Physician Champions, Institutional Issues, Brochure or Flyer, Cancer

Highlights

Establishing the necessary resources and appropriate culture resulted in an accrual increase of over 75%. 

Why this item may be useful

The goal of the campaign was to achieve a 40% increase in accrual over a 2-year period. The critical elements of change implemented at this cancer center included education of stakeholders, enhancement of Disease-Specific Committees, upgraded operations, and increased leadership engagement. Elements were implemented simultaneously to complement each other and form a unified approach. The increase in overall accruals was robust and persistent over time. 

Details

4 key areas of emphasis:

  • tasking leadership with increased oversight of the entire process;
  • education of all stakeholders as to the purpose, advantages, and availability of clinical trials; 
  • increased oversight of the portfolio of clinical trials by Disease-Specific Committees;
  • optimization of accrual operations and infrastructure center-wide. 

The accrual goal was achieved 4 months ahead of schedule at this comprehensive cancer center. The therapeutic accrual rate increased from below 15% to over 25%.