A Comprehensive Program for the Enhancement of Accrual to Clinical Trials
Establishing the necessary resources and appropriate culture resulted in an accrual increase of over 75%.
Why this item may be useful
The goal of the campaign was to achieve a 40% increase in accrual over a 2-year period. The critical elements of change implemented at this cancer center included education of stakeholders, enhancement of Disease-Specific Committees, upgraded operations, and increased leadership engagement. Elements were implemented simultaneously to complement each other and form a unified approach. The increase in overall accruals was robust and persistent over time.
4 key areas of emphasis:
- tasking leadership with increased oversight of the entire process;
- education of all stakeholders as to the purpose, advantages, and availability of clinical trials;
- increased oversight of the portfolio of clinical trials by Disease-Specific Committees;
- optimization of accrual operations and infrastructure center-wide.
The accrual goal was achieved 4 months ahead of schedule at this comprehensive cancer center. The therapeutic accrual rate increased from below 15% to over 25%.